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Research paper published: Antibacterial PHAs-Se/Sr Co-substituted Hydroxyapatite Composites for Bone Regeneration.
The research was jointly carried out by Dr. Elena Marcello and Dr. Muhammad Maqbool, under the supervision of Prof. Ipsita Roy (University of Sheffield) and Prof. Aldo Boccaccini (FAU Erlangen).
Leiden, April 2021
CAM Bioceramics would like to congratulate all authors on the publication of their research paper ” Antibacterial Composite Materials Based on the Combination of Polyhydroxyalkanoates With Selenium and Strontium Co-substituted Hydroxyapatite for Bone Regeneration”. We are particular proud of Dr. Muhammad Maqbool, scientist at CAM Bioceramics for his contributions.
Antimicrobial resistance (AMR) can lead to revisions which causes pain to many patients and are a burden on healthcare systems worldwide. The work focused on tackling the worldwide threat posed by the rapid growth of antimicrobial resistance to antibiotics. It highlights that the combination of PHA and hydroxyapatite in conjunction with selenium and strontium ions has great potential in the design of novel antibacterial scaffolds to provide antibacterial activity without the use of antibiotics, allowing them to be used as starting materials for the development of unique and effective antibacterial scaffolds for bone regeneration.
“in line with CAM Bioceramics mission, to be the trusted partner for innovative calcium phosphate solutions and services worldwide, aims to assist our customers to improve patient live. Finding novel materials for biomedical applications capable of providing antibacterial properties without the use of any drugs. will significantly improve patients outcomes and reduced cost to society.
The paper can be found using the link below:
https://www.frontiersin.org/articles/10.3389/fbioe.2021.647007/full
As communicated in November 2020 CAM Bioceramics is an industry partner and a work package leader of NWO funded DARTBAC Project. The DARTBAC project focuses specifically on the development and testing of the efficacy and safety of novel antimicrobial materials for preventing & combatting infection.
Further information about the DARTBAC project can be found at: https://www.cambioceramics.com/news/dartbac-project-grant-approval-leiden-november-2020-2/
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Products
CAM Bioceramics is a contract development and manufacturing company of Orthobiologic Calcium Phosphates. Our compositions are made from Hydroxyapatite, β-TCP, α-TCP and Biphasic HA/TCP.
Our products are available as coating powders, specialty powders, granules, blocks, and as excipients. Customized calcium phosphates are developed by our highly specialized engineers upon customer request.
Coating powder
Activities
Co-Development
Product development has a key role in our organization. Our specialized engineers develop customized products and revolutionary new biomaterials. As calcium phosphate experts, we assist industry leaders in finding the right product mix and up-scaling into production.
Customized Cleanroom Packaging
Our class-7 cleanrooms, bioburden measurements and excellently trained staff enable us to provide our clients with full-service, customized packaging activities.
HA Plasma-Sprayed Coating Services
CAM Bioceramics is a worldwide pioneer in HA plasma-sprayed coatings. We are specialized in the most challenging and demanding orthopedic and dental implants.
In the 1980s, we were the first company to develop and commercially produce innovative HA plasma-sprayed coatings on orthopedic implants. Since then, our pioneering work has led to the worldwide adoption of hydroxyapatite coatings. HA Coating was the first step in the formation of what is now an established research, manufacturing, packaging and consultancy organization with an extensive portfolio of orthobiologic calcium phosphates.
As a dedicated contract development and manufacturing organization, we have set up robust processes to manufacture a wide range of products for industry leaders in the orthopedic, dental and aesthetic markets. Our offices and in-house production facilities are located in Leiden Bio Science Park, a leading life sciences cluster. Situated close to Amsterdam Schiphol Airport and other major European and global logistics hubs, we provide a highly reliable service to customers all over the world.
Quality
CAM Bioceramics provides calcium phosphates and related services that consistently meet customer needs and regulatory requirements applicable to medical devices and related services.
The CAM Bioceramics quality management system has been developed based on ISO 13485:2016.
Applications
Orthopedic implants
CAM Bioceramics’ powders are widely used in the orthopedic industry for plasma-sprayed implant coatings.
Bone graft substitutes
CAM Bioceramics calcium phosphate powders, granules, blocks and putties are used for synthetic bone grafts, as a filler for gaps and voids in the treatment of fractures and major bone defects.
Bioresorbable fixation
CAM Bioceramics calcium phosphate products are applied as material for bioresorbable fixation systems such as interference screws and suture anchors.
Dental
CAM Bioceramics specialized dental products include dental bone grafts and implant coatings.
Aesthetics
CAM Bioceramics hydroxyapatite is used as an injectable dermal filler.
Excipients
CAM Bioceramics calcium phosphates are used as a carrier for active ingredients for a targeted delivery and controlled release.
