Research paper publication: Antimicrobial activity of ion-substituted calcium phosphates: A systematic review


CAM Bioceramics would like to congratulate Robert Kamphof (PhD Student at CAM), Rui N.O. Lima (CAM intern) & Dr Giuseppe Cama, Head of R&D at Cam Bioceramics. and all co-authors on the publication of their research paper: Antimicrobial activity of ion-substituted calcium phosphates: A systematic review.

Infections surrounding bone implants are an important challenge for advanced reconstructive surgery. Bacteria are becoming more resistant to drugs and there are fewer effective antibiotics to fight against pathogens. Antimicrobial resistance (AMR) is one of the top 10 global health threats which can lead to implant revision which causes pain to patients and places a strain on healthcare systems worldwide.

The project aimed to address the global challenge posed by the fast spread of antimicrobial resistance to antibiotics. The findings demonstrate that ion-substituted calcium phosphates hold great promise for the development of novel antibacterial materials. These materials provide antibacterial activity without the use of antibiotics, allowing them to be used as starting materials for the development of unique and effective antibacterial implants for bone regeneration.

“In line with CAM Bioceramics mission, to be the trusted partner for innovative calcium phosphate solutions and services worldwide, we are committed to support our customers to improve patients lives. Identifying and developing novel materials for biomedical applications that can provide antibacterial properties without the use of any drugs, will significantly improve patients outcomes and reduce cost to society.

The paper can be found using the link below:

As communicated in November 2020, CAM Bioceramics is an industry partner and a work package leader of NWO funded DARTBAC Project. The DARTBAC project focuses specifically on developing and testing the efficacy and safety of novel antimicrobial technologies for preventing & combatting infections.

Further information about the DARTBAC project can be found at: